Data from nuclear diagnostics present correlated signatures of azimuthal implosion asymmetry in recent indirect-drive inertial confinement fusion (ICF) implosion campaigns performed at the National Ignition Facility (NIF). The mean hot-spot velocity, inferred from the Doppler shift of 14 MeV neutrons produced by deuterium-tritium (DT) fusion, is systematically directed toward one azimuthal half of the NIF target chamber, centered on ϕ≈70°. Areal density (ρR) asymmetry of the converged DT fuel, inferred from nuclear activation diagnostics, presents a minimum ρR in the same direction as the hot-spot velocity and with ΔρR amplitude correlated with velocity magnitude. These two correlated observations, which are seen in all recent campaigns with cryogenic layers of DT fuel, are a known signature of asymmetry in the fuel convergence, implying a systematic azimuthal drive asymmetry across a wide range of shot and target configurations. The direction of the implied radiation asymmetry is observed to cluster toward the hohlraum diagnostic windows. This low-mode asymmetry degrades hot-spot conditions at peak convergence and limits implosion performance and yield.