If you don't have a 3.7 for @dataclass and need mutability, the following code might work for you. It's quite self-documenting and IDE-friendly (auto-complete), prevents writing things twice, is easily extendable and it is very simple to test that all instance variables are completely initialized:
class Params():
def __init__(self):
self.var1 : int = None
self.var2 : str = None
def are_all_defined(self):
for key, value in self.__dict__.items():
assert (value is not None), "instance variable {} is still None".format(key)
return True
params = Params()
params.var1 = 2
params.var2 = 'hello'
assert(params.are_all_defined)