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Saloni
21.6K posts
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Saloni
@salonium
Co-founder & editor @WorksInProgMag. Writer, Scientific Discovery. Podcaster, Hard Drugs. Advisor, @coeff_giving. // Prev @OurWorldInData. 🏳️‍🌈
London, England
scientificdiscovery.dev
Joined January 2013
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  • Pinned
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    Saloni
    @salonium
    May 27
    Guys, how do you invent a vaccine? Or wilder, how do you invent a vaccine during your PhD?! In a new episode of Hard Drugs, we talked to someone who did just that: @Kat_a_Collins! A single malaria parasite that reaches your liver is enough to cause an infection. Worse, malaria
    00:00
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    Saloni
    @salonium
    Jul 26, 2023
    I graduated with my PhD today :)
    270K
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    Saloni
    @salonium
    Jun 5, 2020
    Me, reading the headline: "Haha, I bet they didn't control for the effects of age." 🤪😝 *clicks link to read the paper* "Holy..., they actually didn't control for age."
    Bald men at higher risk of severe case of Covid-19, research finds
    From telegraph.co.uk
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    Saloni
    @salonium
    Oct 23, 2022
    There are many examples of medical knowledge that I think everyone should know. This is one of them.
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    Saloni
    @salonium
    May 15, 2023
    You often hear that full siblings "share 50% of their DNA." But did you know this is actually the median and the range is pretty wide, roughly between 40–60%? journals.plos.org/plosgenetics/a… isogg.org/wiki/Autosomal…
    1.3M
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    Saloni
    @salonium
    Aug 22, 2024
    I read this recent 'microplastics in the brain' article and I have a lot of questions. 🧵
    user avatar
    Douglas Main
    @Douglas_Main
    Aug 21, 2024
    My first story for @guardian / @thenewledenews: Microplastics are turning up in more & more human organs — including the brain. (Thread...) theguardian.com/environment/ar…
    1.9M
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    Saloni
    @salonium
    Feb 19, 2023
    Many know that the Carter Center, founded by Jimmy Carter, has been working towards eradicating neglected diseases like Guinea worm. But fewer know how successful this has been. In 1989, there were >890,000 cases worldwide. In 2021, there were 15. ourworldindata.org/guinea-worm-pa…
    Chart showing the decline in reported cases of guinea worm disease from 1986 to 2021. Cases of guinea worm disease declined rapidly across many countries. Over 890,000 cases were recorded worldwide in 1989. By 2021, there were just 15. Almost all of the 15 cases were recorded in Chad.
    310K
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    Saloni
    @salonium
    Dec 23, 2024
    Many people talk about the 'Golden Age of Antibiotics' but I hadn't seen it visualized properly. How abundant was antibiotic development during that time period? How many types of antibiotics were developed? So I visualized it myself!
    A timeline titled "The Golden Age of Antibiotics" shows when each antibiotic drug class was first available for medical use, with example antibiotics labeled. Classes are color-coded by their source: actinomycetes, other bacteria, fungi, or synthetic. Milestones include the first antibiotics (arsphenamines in 1910), as well as the discovery of many actinomycetes-derived antibiotics, such as streptomycin, and sulfonamides, penicillins, and tetracyclines. Data: Hutchings, Truman, Wilkinson (2019). Created by Saloni Dattani for Our World in Data.
    259K
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    Saloni
    @salonium
    Oct 25, 2022
    Here's a statistic that everyone should know. wired.com/story/covid-19…
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    Saloni
    @salonium
    Jun 17, 2025
    Has nominative determinism gone too far (h/t @bschne)
    149K
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    Saloni
    @salonium
    Dec 10, 2024
    Americans are now one-third less likely to die from cancer at the same ages as Americans in 1990
    How has the risk of dying from cancer changed in the United States?

To understand this, we can look at national cancer death rates in the United States.

The gray line shows the crude rate, which is the rate of deaths from cancer per 100,000 people. It has risen between 1950 and 1990 and has fallen slightly since then.

However, cancer death rates rise sharply with age, and the age of the US population has increased since 1950, so we would expect cancer death rates to rise for that reason alone.

What if we adjust for the increased age of the US population?

The red line, the age-standardized rate, shows this. It shows the cancer death rate if the age structure of the US population was held constant throughout.

This shows a slight rise until 1990 and then a significant decline; rates have fallen by one-third.

This means Americans are now one-third less likely to die from cancer at the same ages as Americans in 1990.
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    Saloni
    @salonium
    May 13, 2024
    New article by me: The rise in reported maternal mortality rates in the US is largely due to a change in measurement. ourworldindata.org/rise-us-matern… The change was adopted by different states at different times, resulting in what appeared to be a gradual rise in maternal mortality.
    581K
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    Saloni
    @salonium
    Jan 15, 2023
    People tend to see cancer as an inevitable part of ageing. What if it's not? The cancer death rate has fallen by 27% in the US over the last two decades! We've not only learnt to treat cancer better, but also how to prevent many cases entirely. cdc.gov/cancer/dcpc/re…
    382K
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    Saloni
    @salonium
    Jul 25, 2024
    Re-upping what's probably the biggest medical breakthrough result this year: A twice-yearly injectible antiviral with an efficacy of 96–100% in preventing HIV.
    user avatar
    Saloni
    @salonium
    Jun 20, 2024
    Big result in HIV antiviral development statnews.com/2024/06/20/hiv…
    Gilead said Thursday that twice-a-year injections of a new antiviral drug, called lenacapavir, completely protected cisgender women from contracting HIV in a large Phase 3 trial.

In the study, none of the 2,134 women who received lenacapavir contracted HIV. By comparison, 16 of the 1,068 women who received the long-running daily pill Truvada contracted HIV. And 39 out of 2,136 women who received a newer daily pill called Descovy developed HIV.
    120K

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