Humanity has nearly destroyed its world through global warming, but now an even greater evil lurks. The indigenous people of North America are being hunted and harvested for their bone marrow, which carries the key to recovering something the rest of the population has lost: the ability to dream. In this dark world, Frenchie and his companions struggle to survive as they make their way up north to the old lands. For now, survival means staying hidden—but what they don't know is that one of them holds the secret to defeating the marrow thieves.

Jacquie Red Feather is newly sober and trying to make it back to the family she left behind in shame. Dene Oxendene is pulling his life back together after his uncle's death and has come to work at the powwow to honor his uncle's memory. Opal Viola Victoria Bear Shield has come to watch her nephew Orvil, who has taught himself traditional Indian dance through YouTube videos and will perform in public for the very first time. There will be glorious communion and a spectacle of sacred tradition and pageantry. And there will be sacrifice, and heroism, and loss.

Saul Indian Horse is in critical condition. Sitting feeble in an alcoholism treatment facility, he is told that sharing his story will help relieve his agony. Though skeptical, he embarks on a heartbreaking journey from the present - and into the woods of Northern Ontario, where his life began in a snowy Ojibway camp. The tale that follows is one of great pain and great determination from Richard Wagamese, an author who "never seems to waste a shot" ( New York Times).

Kirsten Raymonde will never forget the night Arthur Leander, the famous Hollywood actor, had a heart attack on stage during a production of King Lear. That was the night when a devastating flu pandemic arrived in the city, and within weeks, civilization as we know it came to an end.

Years ago, when plagues and natural disasters killed millions of people, much of the world stopped dreaming. Without dreams, people are haunted, sick, mad, unable to rebuild. The government soon finds that the Indigenous people of North America have retained their dreams, an ability rumored to be housed in the very marrow of their bones. Soon, residential schools pop up — or are re-opened — across the land to bring in the dreamers and harvest their dreams.