The Big One Audiobook By Michael T. Osterholm PhD MPH, Mark Olshaker cover art

The Big One

How We Must Prepare for Future Deadly Pandemics

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The Big One

By: Michael T. Osterholm PhD MPH, Mark Olshaker
Narrated by: Peter Ganim
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As bad as Covid-19 was, the next pandemic could be worse—but we have the tools to prepare, as revealed in this urgent, gripping warning by the New York Times bestselling authors of Deadliest Enemy.

The Covid-19 pandemic was the most devastating natural event of the last century, killing more than 7 million people around the globe, straining the fabric of societies internationally, and shaking the foundations of the global economy. And yet, as horrifying as the experience was, Covid-19 was not actually “the Big One”—the dreaded potential pandemic that haunts the nightmares of epidemiologists and public health officials everywhere, and which will alter life across the world on every meaningful level unless we are ready to deal with it. Indeed, even as we learn to live with Covid-19 and continue to recover from its worst effects, the next pandemic is already lurking around the corner—and it may very well be worse.

In The Big One, founding director of the Center for Infectious Disease Research and Policy Michael T. Osterholm and Mark Olshaker examine past pandemics, highlighting the ways societies both succeeded and failed to address them; trace the Covid-19 pandemic and evaluate how it was handled; and look to the future, projecting what the next pandemics might look like and what must be done to mitigate them. Drawing on years of high-level research as well as cutting-edge analysis and an innovative hypothetical scenario threaded throughout each chapter, The Big One is a gripping, comprehensive, and urgent wake-up call. Because Covid-19 was just a taste of what’s to come. If we’re going to survive the next big pandemic, we need to be prepared.

©2023 Michael Osterholm and Mark Olshaker (P)2023 Little, Brown Spark
Biological Sciences Medicine & Health Care Industry Physical Illness & Disease Policy & Administration Science

Critic reviews

“With his unique blend of knowledge, communications skills, and Midwestern forthrightness, Michael Osterholm has made himself indispensable in the fight to understand and overcome global infections. In The Big One, he marshals this depth and breadth to prepare us for the struggle that surely will come.”—Peter Hotez, Baylor College of Medicine, and author of The Deadly Rise of Anti-Science

“If there was one person to turn for future pandemic readiness, it would be Michael Osterholm, one of the world’s leading epidemiologists. In The Big One, a landmark book, he, along with Mark Olshaker, provide a remarkably clear-eyed, science-driven, and comprehensive preventive approach.”—Eric Topol, MD, PhD, author of Deep Medicine and Super Agers

“Mike Osterholm is an invaluable expert whose tremendous knowledge and humility also make him a trustworthy guide. In The Big One, Osterholm and Mark Olshaker take us through a tabletop exercise about a highly contagious, airborne virus capable of killing millions. We can only hope those in power heed its guidance.”—Ezekiel J. Emanuel, MD, PhD, author of Reinventing American Healthcare

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Ideally, everyone who can read should read this, but since that won’t happen, those who do read it have a responsibility to disseminate at least parts of it whenever we can to those who might listen. Members of the media especially have a responsibility to report facts rather than just inflammatory opinions that get them more clicks. Dr. Osterholm’s expertise after a lifetime of experience make him an extremely credible source for these facts. His recommendations for future planning are the best we can do based on what we know now.

The volume and depth of the information provided.

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The hypothetical Big One is a logical extension of what we've already gone through over the last five years. And the authors draw extensively from what happened and what should have happened during Covid. Yet I fear no lessons have been learned and planning for The Big One has already gone out the window on the instructions of RFK Jr.

Hell awaits!!!

Horrific and predictable

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Excellent story construction, using table top exercise ays a basis for content development. The narrator is TERRIBLE: weird, inappropriate slow downs and word emphasis. If the book’s content hadn’t been so interesting, I would have quit.

Terrible narrator - great book

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Comprehensive and not to be missed if you really want to know what happened and what needs to be done that wasn’t and isn’t. A must read. Sadly ,those that should read it probably won’t.

Important well written and detailed

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The author’s experience and expertise shows a path forward where we could improve our odds of weathering the Big One. Unfortunately these lessons are being ignored to the risk of our health. The lessons he gives is a path forward with the best evidence today and knowing that recommendations must be able to change depending on what is happening. A general knows his best laid battle plans will change once a conflict starts.

Very educational and too true

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