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(−)-menthol dehydrogenase

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(−)-menthol dehydrogenase
Identifiers
EC no.1.1.1.207
CAS no.81811-46-3
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

(−)-Menthol dehydrogenases (EC 1.1.1.207) are a type of enzyme found in mint plants (mentha)[1] that catalyzes the chemical reaction

 
 
 
H+
Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right
 
H+
 
 

The two substrates of this enzyme are (−)-menthol and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are (−)-menthone, reduced NADPH, and a proton.[2][3]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (−)-menthol:NADP+ oxidoreductase. This enzyme is also called monoterpenoid dehydrogenase. This enzyme participates in monoterpenoid biosynthesis.

See also

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References

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  1. ↑ BRENDA online database for enzymes: 1.1.1.207
  2. ↑ Enzyme 1.1.1.207 at KEGG Pathway Database.
  3. ↑ Kjonaas R, Martinkus-Taylor C, Croteau R (May 1982). "Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves". Plant Physiology. 69 (5): 1013–7. doi:10.1104/pp.69.5.1013. JSTOR 4267341. PMC 426349. PMID 16662335.