Analysis scripts and relative data used in the paper "Genome-wide hypomorphic variants of short-segment Hirschsprung disease conform to an omnigenic model" by Han et al.

rare_mutaion_landscape.R This script is used to draw the heatmap which displays the landscape of the rare variants detected in 453 known HSCR- and ENS-related genes or 222 related genes.

contains the config file and circos figure for the distribution of the DE genes on chromosomes.