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Guido Appenzeller
a16z
3,639 posts
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Guido Appenzeller
a16z
@appenz
At a16z investing in AI & Infra. 2x founder & CEO. CTO at Intel & VMware. CPO at Yubico. Tweets are my own.
Silicon Valley, CA
guido.appenzeller.net
Joined January 2008
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  • Pinned
    user avatar
    Guido Appenzeller
    a16z
    @appenz
    Jun 25
    Super excited to announce that we are leading the Series A in @netris_io. Every technology cycle changes the underlying infrastructure. And Netris has build the Networking Software Stack for AI. We are excited to partner with @alex_saroyan, Arsen Arakelyan and Tigran Martirosya!
    Investing in Netris | Andreessen Horowitz
    From a16z.com
    3.6K
  • user avatar
    Guido Appenzeller
    a16z
    @appenz
    9h
    If you extrapolate this data, we should have a model that can do agentic reasoning (~ Opus 4.6 quality) running on an iPhone by May 2027. Crazy. Credit /u/No-Meringue5867 on @Reddit.
    1.3K
  • user avatar
    Guido Appenzeller
    a16z
    @appenz
    Jul 30
    The ratio of input to output tokens for my LLM usage last week was 300:1. Crazy how agents have changed LLM workloads. All of you fearless AI infra engineers that manage K/V caches, we salute you!
    795
  • user avatar
    Guido Appenzeller
    a16z
    @appenz
    Jul 28
    The so called "safety" tuning of models is a mess. It never blocks you, it just kills usability. Example from GPT-5.6-Sol below. Protecting PII always has to happen in the harness. It's nuts to try and do this in the model because (1) you don't know the use case yet and (2)
    904
  • user avatar
    Guido Appenzeller
    a16z
    @appenz
    Jul 26
    Denny’s marketing 🔥
    user avatar
    Denny’s
    @DennysDiner
    Jul 25
    Replying to @JensenHuang and @nvidia
    862